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Leukemia: Cause -Symptoms -Acute-Chronic leukemia diagnosis-in detail !

Have a close friend, exercise every day Always good health, with nosebleeds How much do not stop Flows half a day The blood test doctor found that There are more than 10 times the normal white blood cell count. Diagnosed with leukemia.

Leukemia: Cause -Symptoms -Acute-Chronic leukemia diagnosis-in detail !
Leukemia: Cause -Symptoms -Acute-Chronic leukemia diagnosis-in detail !

Leukemia It is a cancer caused by white blood cells. The embryo in the bone marrow grows faster than normal.

And become abnormal cells Can not grow into the old white blood cells that do normal functions In addition, it is still old and slower than usual.

Can spread to infiltrate various organs such as lymph nodes, liver, spleen, bones, brain, testicles, skin, including infiltration in the bone marrow Destroy red blood cells, white blood cells and platelets in the bone marrow Causing various symptoms and complications Until dangerous to death


There are many types of leukemia, mainly divided into

* Acute type (Which is caused by embryonic cells With sudden symptoms Aggressive and severe) were A. LLP (ALL or acute lymphoblastic leukemia) and AMD L. (AML or acute myeloblastic leukemia).

* Chronic type (which is caused by white blood cells that become old Symptoms progress slowly and incrementally) include DC LLP (CLL or chronic lymphocytic leukemia) and CMG plc (CML, or chronic myelocytic leukemia).* Thai name
Leukemia Leukemia* English name
LeukemiaContent Contents
There are many types of leukemia , mainly divided into

* Cause
* symtoms
* Disease isolation
* diagnosis
* self - care
* treatment
* Complications
* Disease progression
* protect
* prevalence

Have a close friend, exercise every day Always good health, with nosebleeds How much do not stop Flows half a day The blood test doctor found that There are more than 10 times the normal white blood cell count. Diagnosed with leukemia.

Leukemia It is a cancer caused by white blood cells. The embryo in the bone marrow grows faster than normal. And become abnormal cells Can not grow into the old white blood cells that do normal functions In addition, it is still old and slower than usual.

Can spread to infiltrate various organs such as lymph nodes, liver, spleen, bones, brain, testicles, skin, including infiltration in the bone marrow Destroy red blood cells, white blood cells and platelets in the bone marrow Causing various symptoms and complications Until dangerous to death


There are many types of leukemia, mainly divided into

* Acute type (Which is caused by embryonic cells With sudden symptoms Aggressive and severe) were A. LLP (ALL or acute lymphoblastic leukemia) and AMD L. (AML or acute myeloblastic leukemia).

* Chronic type (which is caused by white blood cells that become old Symptoms progress slowly and incrementally) include DC LLP (CLL or chronic lymphocytic leukemia) and CMG plc (CML, or chronic myelocytic leukemia).* Thai name
Leukemia Leukemia

* English name

Leukemia

* Cause  

Most of them do not know the exact cause. Believe that there are abnormal genetic factors Together with environmental factors Some patients find that there are factors that cause this important disease, such as

* The presence of abnormal genes such as Down's syndrome, a type of mental retardation disorder, has a risk of acute leukemia. (Both ALL And AML) more than normal people
People with chronic leukemia CML type Found abnormal chromosomes
Or those who have direct relatives with acute lymphoblastic leukemia

* People who have a history of receiving radiation therapy or chemotherapy to treat other types of cancer first Some people may find leukemia a few years later.

* People with a history of nuclear radiation exposure (such as those who survived the atomic bomb Or accidents from nuclear power plants) or benzene Found that the risk of leukemia is higher than the average person

* Infection with HTLV-1 virus (HTLV-1) has been found to be associated with the occurrence of adult T-cell leukemia .

* Symptoms

* Acute leukemia (ALL and AML) often have sudden symptoms with fever, pale or green bruise on the body or bleeding in places such as nosebleeds. Scurvy Menstrual period is very unusual. Blood
Some people may have fever, aches, flu-like symptoms, fatigue, weight loss, may be chronic fever as a month. Or chills With eczema in the mouth, tonsillitis or pneumonia due to low immunity
 May come to see a doctor with the symptoms of green puffiness Or having nosebleeds that is hard to stop Due to low platelets

At a later stage, often have anemia, weakness, fatigue may have mental symptoms (such as headaches, dizziness, vomiting, seizures, eye) distension, abdominal pain due to hepatomegaly, splenomegaly
may have specific symptoms such as bone pain and bulging eyes. Swollen gums, etc.


* Chronic leukemia (CLL and CML) in the early stages, mostly without symptoms Which may last a year and often check the blood, found that this disease accidentally
In cases of symptoms (Which is often a disease in the later stages) will have fatigue, easy fatigue, loss of appetite, weight loss, fever, night sweats Feeling distressed due to the spleen
Later, there will be pale symptoms. With a green body or easy bleeding Bone and joint pain similar to acute leukemia patients

At the end, there are often infectious diseases. May be caused by viruses (Commonly found as shingles) bacteria (such as Sudodenase Kelsila) or fungus (such as Candida Aspergillus)


* Disease isolation

* Symptoms of fever, pale and green pimples May be caused by other causes such as anemia, aplastic anemia, septicemia, etc.
* Symptoms with red spots, cyanosis or various bleeding (eg nosebleeds Scurvy Blood transfusion) may be caused by other causes such as thrombocytopenia Hemophilia (One type of simple bleeding disease that is inherited) antiplatelet (eg, aspirin, which is commonly used in diabetic patients Coronary artery disease Hemiplegia)

* Symptoms of enlarged lymph nodes (There is a swollen lump in the neck, armpit, groin) which may be detected in patients with acute leukemia May be caused by other types of cancer (such as cancer of the throat, lymphoma)

* diagnosis

The doctor will make a preliminary diagnosis of symptoms including chronic fever (longer than 1 week), pale green blotches Bleeding at various places Multiple lymph nodes, liver, spleen, splenomegaly, which will confirm the diagnosis by blood test.

 Found more than normal white blood cells (usually 5,000 - 10,000 / mm3, this disease will find tens of thousands of white blood cells per 1 millimeter of blood and is found as more than normal embryonic cells ) And may find the number of red blood cells And platelets below normal
Bone marrow examination will find many embryonic cells .

* Self-care

If there are suspicious symptoms such as fever for weeks, pale red spots, green spots Abnormal bleeding (eg hard nosebleeds Scurvy Blood transfusions), palpation, swelling of the neck, armpit or groin, etc. should seek medical advice

If found to be leukemia Should follow up with the doctor seriously and continuously especially Must endure the side effects of treatment (such as hair loss, nausea, vomiting, loss of appetite) that may occur. Which is usually only temporary

Do not leave the hospital's treatment arbitrarily. Or turn to the treatment method .

* treatment

In addition to providing symptomatic treatment and correcting complications (such as giving blood, treating infections with antibiotics or antimicrobial agents), a specialist in blood diseases (hematology) and cancer provides chemotherapy (Cancer medicine) There are many groups, many types of which the doctor will choose to use as appropriate for the type and severity of the disease. Most will use at least 2 groups together.

In addition, other drugs are also used in combination with chemotherapy such as anti-inflammatory agents, monoclonal antibody, stimulants for white blood cell production and red blood cells.

Some people with very swollen lumps (such as enlarged lymph nodes, hepatomegaly, splenomegaly, testicular stones) caused by cancer cells to accumulate May require radiation (radiotherapy) as well
Some doctors may perform bone marrow transplantation or stem cells, especially in cases of relapse. After a period of calm after chemotherapy Back to top Back to top .

* Complications

Common complications include bleeding and severe infections. The serious danger of death is Bleeding in the brain And septicemia
In cases of acute leukemia Aml type Blood clotting may occur throughout the body. (disseminated intravascular coagulation or DIC) is a serious danger

In cases of acute lymphoblastic leukemia, there may be thymus gland presses the air duct (Makes breathing difficult) or the upper vena cava causes swollen neck and arms
In cases of chronic lymphoblastic leukemia, it may become a serious type of lymphoma. Or have lung cancer Or subsequent skin Back to top Back to top .

* Disease progression

 If not treated Often cause serious complications Can cause death
 The patients who received treatment Treatment results depend on the type of cancer, the stage of the disease and the patient's condition as follows.

* For patients with acute lymphoblastic leukemia (ALL), if not treated, usually die within 4 months, chemotherapy can destroy cancer cells until the disease is calm Continuous treatment helps 80 percent of sick children and 30-40 percent of adults get sick from the disease.
In cases of relapse Doctors need chemotherapy, radiation therapy, and may need bone marrow transplantation or stem cells.

* For patients with acute leukemia AML type, if not treated, usually dies within a few weeks to a few months. Treatment can calm the disease by 70-80 percent of patients under the age of 60. People over 65 years of age or have this disease after receiving chemotherapy or radiation therapy to treat other cancers before the results. Treatment is usually not good.

* For patients with CLL ( chronic lymphoblastic leukemia ), if detected and treated in the early stages of the disease, they will often live longer than 10-20 years. Work and study as usual But if found at the end stage, may live for 3-4 years

* For patients with chronic leukemia CML type (50 percent) lives for more than 4-5 years. Approximately 20 percent die within 2 years. Those who have received bone marrow transplantation or stem cells Can recover from the disease by up to 60 percent .



* protect

 There is no way to prevent this disease. Because most occur without knowing the cause.
Important. When suspicious symptoms should rush to check with the doctor seriously and continuously. To prevent complications Back to top Back to top .

* prevalence

This disease can be found in people of all ages. But the symptoms in children or adults are different as follows:
* Acute leukemia type AL (ALL) is more common in children aged 2-5 years (found up to 80 percent of leukemia in children) and may be found In adults, especially over the age of 65
* Acute leukemia AML type is the most common type. And found in adults rather than children
* Chl type C leukemia is common in adults. And the prevalence of the disease increases with age Found in groups over the age of 60

* Chronic leukemia CML type (CML) is a rare type. Commonly found in adults aged 30-40 years. Less common in children under 10 years old.

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Leukemia: Cause -Symptoms -Acute-Chronic leukemia diagnosis-in detail ! Leukemia: Cause -Symptoms -Acute-Chronic leukemia diagnosis-in detail ! Reviewed by Health-nutrition-fitness.net on June 14, 2019 Rating: 5

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